Is it hard to change the way you are after high school?

I've had a rough time in high school. Never really talked to anybody and was always shy. I never really dated any girl in school and didn't even go the prom or senior trip because I had no friends. I'm hoping to change the way I am so when I'm done with college I'll have memorable moments that will make up for everything that I missed out on in high school. I'm hoping but than again there's times when I think about high school and going to college and I just say to myself "damn another chapter to the book where I'm probably going to live miserably again". Do you think it's hard for people to change once they start college and is college any different?